SCHEMBL28029977

SCHEMBL28029977

COP(=O)(OC)OC(=Cc1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 1/20 0.44
AKR1C3 P42330 1/20 0.44
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
CASP3 P42574 3/20 0.41
SENP7 Q9BQF6 3/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
ABCB1 P08183 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
EGFR P00533 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28029975 0.86 AKR1C3 (0.44) AKR1C3NPC1RAB9ACASP3SENP7
SCHEMBL28029985 0.84 MEN1 (0.44) AKR1C3MEN1KMT2AKDM4EALDH1A1
SCHEMBL28029983 0.84 MEN1 (0.44) AKR1C3MEN1KMT2AKDM4EALDH1A1
SCHEMBL28029976 0.80 MAPT (0.45) CYP1B1AKR1C3MEN1KMT2AKDM4E
SCHEMBL28030361 0.80 PTGS2 (0.42) NPC1RAB9APTGS2MEN1KMT2A
SCHEMBL28822075 0.80 CYP1B1 (0.42) CYP1B1AKR1C3NPC1RAB9APTGS2
SCHEMBL28030357 0.80 MAOB (0.43) AKR1C3NPC1RAB9AMEN1KMT2A
SCHEMBL28029986 0.77 KMT2A (0.44) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL28029993 0.76 P4HB (0.44) KMT2AKDM4EALDH1A1PKM
SCHEMBL22493010 0.75 AKR1C1 (0.46) CYP1B1AKR1C3NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104926867-A Preparation method for alkenyl phosphate compound UNIV BEIJING 2015-09-23 CN disclosed