Phenol

Phenol

SCHEMBL28030104

CCCO[N+](=O)[O-].Oc1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.42
LMNA P02545 1/20 0.41
PTGS2 P35354 2/20 0.40
PTGS1 P23219 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 2/20 0.40
ESR1 P03372 1/20 0.40
CHRM1 P11229 1/20 0.40
TSHR P16473 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDR P35968 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
GLA P06280 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27746061 0.88 ESR2 (0.47) ESR2LMNAPTGS2ALDH1A1TSHR
SCHEMBL324772 0.78
Bromide SCHEMBL27445705 0.76
Ammonia Solution, Strong SCHEMBL7763468 0.76
Water SCHEMBL7212356 0.76
Nitric Acid SCHEMBL28123755 0.74 CA5A (0.38) PTGS2ALDH1A1TSHRCA12CA1
Phenol SCHEMBL27570167 0.74 TDP1 (0.52) ESR2LMNAPTGS2PTGS1TDP1
Ethylene SCHEMBL31157037 0.74
Pyrrole SCHEMBL28216010 0.73 ALDH1A1 (0.33) ESR2LMNAPTGS2ALDH1A1CA12
Phenol SCHEMBL450290 0.72 TDP1 (0.50) ESR2LMNAPTGS2PTGS1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377830-A 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic) pyrimidine-4-carboxylates and their use as herbicides DOW AGROSCIENCES LLC 2016-03-02 CN disclosed
CN-105377816-A Pyridine-2-carboxamides as nematocides SYNGENTA PARTICIPATIONS AG 2016-03-02 CN disclosed
CN-105017240-A Pesticidal compositions DOW AGROSCIENCES LLC 2015-11-04 CN disclosed