Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628368 | 0.81 | PNP (0.41) | LMNAACP3PNPMEN1KMT2A | |
| SCHEMBL29818916 | 0.80 | HIF1A (0.54) | ADRB3ADRB1ADRB2LMNAMEN1 | |
| SCHEMBL2150979 | 0.80 | CPN1 (0.44) | ADRB3ADRB1ADRB2IDO1 | |
| SCHEMBL17735447 | 0.80 | HIF1A (0.54) | ADRB3ADRB1ADRB2LMNAMEN1 | |
| SCHEMBL16032729 | 0.80 | CPN1 (0.44) | ADRB3ADRB1ADRB2IDO1 | |
| SCHEMBL2151108 | 0.80 | HIF1A (0.54) | ADRB3ADRB1ADRB2LMNAMEN1 | |
| SCHEMBL2879198 | 0.79 | ADRB3 (0.49) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL767795 | 0.79 | ADRB3 (0.49) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL1154749 | 0.79 | ADRB3 (0.49) | ADRB3ADRB1ADRB2SLC2A1IDO1 | |
| SCHEMBL21848098 | 0.79 | PNP (0.42) | ACP3PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105992767-A | Wnt pathway modulators | 新加坡科技研究局 | 2016-10-05 | — | — | CN | disclosed |
| CN-103429593-B | Imidazopyrazines | HOFFMAN-LA ROCHE LTD. (CH) | 2015-09-09 | — | — | CN | disclosed |