SCHEMBL28030213

SCHEMBL28030213

CC(=O)NBr.CC(=O)NBr

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 1.00
KDM4E B2RXH2 2/20 0.50
CA2 P00918 1/20 0.50
PTGS1 P23219 1/20 0.50
MMP12 P39900 1/20 0.50
LMNA P02545 2/20 0.42
ALDH1A1 P00352 3/20 0.40
CRBN Q96SW2 1/20 0.39
TSHR P16473 4/20 0.39
THPO P40225 1/20 0.39
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
TRPA1 O75762 1/20 0.38
CA1 P00915 2/20 0.36
ALOX15 P16050 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
TAS2R38 P59533 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1658 1.00
Water SCHEMBL571469 0.96
Sulfur Dioxide SCHEMBL10838367 0.89
SCHEMBL5754147 0.72
Acetone SCHEMBL28589505 0.70
SCHEMBL1276127 0.67
SCHEMBL2401765 0.67 KDM4E (0.54) NFKB1KDM4ECA2PTGS1MMP12
Acetohydroxamic Acid SCHEMBL14492 0.67
Diacetamide SCHEMBL97089 0.67
SCHEMBL20411614 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017172-A Halogenous photoactive 2-carbonyl-1,3-oxazine compound and preparation method therefor and application thereof CHINESE ACAD INST CHEMISTRY 2015-11-04 CN claimed