SCHEMBL28030309

SCHEMBL28030309

Cc1cc(C#N)ccc1-n1cncn1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 9/20 0.43
CYP11B1 P15538 4/20 0.42
CYP11B2 P19099 4/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C19 P33261 2/20 0.42
TSHR P16473 1/20 0.42
EGLN2 Q96KS0 5/20 0.40
ADORA3 P0DMS8 2/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
DPP4 P27487 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27971838 0.81 CYP19A1 (0.45) CYP19A1CYP11B1CYP11B2CYP3A4CYP2C19
SCHEMBL12905110 0.81 CYP19A1 (0.43) CYP19A1CYP11B1CYP11B2CYP3A4CYP2C19
SCHEMBL28030310 0.79 CYP19A1 (0.40) CYP19A1CYP11B1CYP11B2CYP3A4CYP2C19
SCHEMBL16944266 0.78 POLB (0.42) CYP3A4CYP2C19CYP1A2CYP2C9
SCHEMBL1955237 0.78 KDM4E (0.43) CYP19A1CYP11B1CYP11B2CYP3A4CYP2C19
SCHEMBL21808491 0.76 EGLN2 (0.41) CYP11B1CYP11B2EGLN2
SCHEMBL6445748 0.76 ALDH1A1 (0.49) CYP3A4CYP2C19ADORA2AADORA1DPP4
SCHEMBL20335460 0.76 L3MBTL1 (0.43) CYP3A4CYP2C19TSHRCYP1A2CYP2C9
SCHEMBL17242393 0.76 APOBEC3A (0.50)
SCHEMBL26031153 0.76 CYP3A4 (0.47) CYP3A4CYP2C19TSHRCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105025715-A Pesticidal compositions and methods related thereto DOW AGROSCIENCES LLC 2015-11-04 CN disclosed
CN-104981155-A Pesticidal compositions and methods related thereto DOW AGROSCIENCES LLC 2015-10-14 CN disclosed
CN-104981160-A Pesticidal compositions and methods related thereto DOW AGROSCIENCES LLC 2015-10-14 CN disclosed