SCHEMBL28030374

SCHEMBL28030374

COP(=O)(OC)OC(=Cc1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.45
NPSR1 Q6W5P4 2/20 0.44
GLA P06280 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAOB P27338 1/20 0.42
ALDH1A1 P00352 4/20 0.39
CYP3A4 P08684 2/20 0.39
TSHR P16473 1/20 0.39
HIF1A Q16665 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CYP2C9 P11712 2/20 0.38
ALOX15 P16050 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28822075 0.94 CYP1B1 (0.42) PTGS2NPSR1GLAMEN1KMT2A
SCHEMBL28029985 0.89 MEN1 (0.44) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL28029983 0.89 MEN1 (0.44) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL28029978 0.85 KMT2A (0.39) NPSR1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL28030362 0.85 PTGS2 (0.45) PTGS2NPSR1MEN1KMT2ACYP2C9
SCHEMBL28030357 0.85 MAOB (0.43) MEN1KMT2AMAOBALDH1A1CYP3A4
SCHEMBL28029984 0.82 ALDH1A1 (0.50) NPSR1GLAMEN1KMT2AALDH1A1
SCHEMBL22493010 0.81 AKR1C1 (0.46) MEN1KMT2AMAOBALDH1A1TSHR
SCHEMBL28030384 0.81 MAOB (0.47) GLAMEN1KMT2AMAOBALDH1A1
SCHEMBL28029994 0.81 MAOB (0.47) GLAMEN1KMT2AMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104926867-A Preparation method for alkenyl phosphate compound UNIV BEIJING 2015-09-23 CN disclosed