Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942183 | 0.77 | SIRT6 (0.87) | SIRT6ADRB1MAPTALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7984519 | 0.76 | SIRT6 (0.84) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL336262 | 0.75 | SIRT6 (1.00) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL7526992 | 0.75 | SIRT6 (1.00) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL6152151 | 0.74 | SIRT6 (0.96) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL6151805 | 0.74 | SIRT6 (0.96) | SIRT6ADRB1MAPTALDH1A1POLB | |
| Hydrogen Sulfide SCHEMBL28002215 | 0.74 | SIRT6 (0.96) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL1496058 | 0.74 | SIRT6 (0.96) | SIRT6ADRB1MAPTALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL1814630 | 0.74 | SIRT6 (0.96) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL5310568 | 0.73 | SIRT6 (0.53) | SIRT6ADRB1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892615-B | Tetrahydro-pyrazole ketone triazin compound and preparation method and application | 河南农业大学 | 2017-04-05 | — | — | CN | disclosed |
| CN-104892615-A | Tetralin pyrazolone triazine compound as well as preparation method and application thereof | UNIV HENAN AGRICULTURAL | 2015-09-09 | — | — | CN | disclosed |