Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 8/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624234 | 0.82 | HDAC8 (0.52) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL6189587 | 0.80 | HDAC8 (0.50) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL9901799 | 0.79 | CA12 (0.42) | HDAC6HPGDALDH1A1 | |
| SCHEMBL235433 | 0.78 | HDAC8 (0.48) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL12615099 | 0.78 | HDAC8 (0.48) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL2680684 | 0.77 | MAPT (0.41) | HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2237100 | 0.77 | RAB9A (0.53) | HPGDSMN1; SMN2 | |
| SCHEMBL1459630 | 0.76 | TDP1 (0.55) | HPGDTSHRHTTSMN1; SMN2CA2 | |
| SCHEMBL745459 | 0.76 | PLK1 (0.55) | HDAC8HDAC6HDAC2HPGDTSHR | |
| SCHEMBL4774336 | 0.75 | ALDH1A1 (0.34) | HDAC6HPGDHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025738-B | Furopyridine compound and uses thereof | NOVARTIS AG (CH) | 2015-08-19 | — | — | CN | claimed |
| CN-103025738-B | Furopyridine compound and uses thereof | NOVARTIS AG (CH) | 2015-08-19 | — | — | CN | disclosed |