Benzene

Benzene

SCHEMBL28030893

COc1ccc(NS(N)(=O)=O)cc1.c1ccccc1

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 13/20 0.92
CA2 P00918 13/20 0.92
PGR P06401 2/20 0.57
LMNA P02545 2/20 0.55
ALDH1A1 P00352 2/20 0.55
GAA P10253 1/20 0.53
MAPK1 P28482 1/20 0.53
CA9 Q16790 3/20 0.52
CA12 O43570 2/20 0.52
ACHE P22303 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1645328 0.96 CA1 (1.00) CA1CA2PGRLMNAALDH1A1
SCHEMBL11708669 0.79 CA1 (0.70) CA1CA2PGRLMNAALDH1A1
SCHEMBL1645211 0.78 CA1 (0.62) CA1CA2LMNAALDH1A1GAA
SCHEMBL4662975 0.78 PGR (0.82) PGRLMNAALDH1A1GAAMAPK1
SCHEMBL171658 0.78 LMNA (0.79) CA1CA2PGRLMNAALDH1A1
Phenylsulfamide SCHEMBL27994318 0.77 CA1 (1.00) CA1CA2ALDH1A1CA9CA12
Phenylsulfamide SCHEMBL253104 0.77 CA1 (1.00) CA1CA2ALDH1A1CA9CA12
SCHEMBL29031235 0.77 PGR (0.85) PGRLMNAALDH1A1GAAMAPK1
SCHEMBL9215868 0.76 CA1 (0.66) CA1CA2PGRLMNAALDH1A1
SCHEMBL21033853 0.76 CA1 (0.66) CA1CA2PGRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104844490-A Method for greenly synthesizing isothiocyanate through two-step method UNIV CHANGZHOU 2015-08-19 CN disclosed