Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29552477 | 0.75 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRL1OPRD1 | |
| SCHEMBL7294202 | 0.75 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRL1OPRD1 | |
| SCHEMBL5838119 | 0.74 | MAOB (0.42) | ALDH1A1OPRM1OPRD1MAOBIDO1 | |
| SCHEMBL15111143 | 0.74 | DDB1 (0.44) | TSHRALDH1A1 | |
| SCHEMBL15106205 | 0.74 | DDB1 (0.44) | TSHRALDH1A1 | |
| SCHEMBL15602797 | 0.71 | TSHR (0.39) | TSHRALDH1A1OPRM1OPRL1OPRD1 | |
| SCHEMBL7076809 | 0.71 | TSHR (0.46) | TSHRALDH1A1OPRM1OPRL1OPRD1 | |
| SCHEMBL9406868 | 0.69 | MAOA (0.39) | OPRM1OPRL1OPRK1MAOB | |
| SCHEMBL16026615 | 0.68 | TSHR (0.43) | TSHRALDH1A1OPRM1OPRL1OPRD1 | |
| SCHEMBL11587465 | 0.67 | TSHR (0.41) | TSHRALDH1A1OPRM1OPRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107105661-A | Big ring picolinamide compound with Fungicidally active | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107105662-A | Big ring picolinamide as fungicide purposes | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-105007732-A | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-10-28 | — | — | CN | disclosed |