Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29552477 | 1.00 | TSHR (0.43) | TSHRALDH1A1IDO1AGXTMAOB | |
| SCHEMBL9182822 | 0.80 | L3MBTL1 (0.48) | TSHRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL6494508 | 0.79 | ALDH1A1 (0.39) | TSHRALDH1A1IDO1AGXTMAPT | |
| SCHEMBL8306987 | 0.78 | MAOB (0.41) | ALDH1A1IDO1MAOB | |
| SCHEMBL27740111 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1IDO1AGXTMAPT | |
| SCHEMBL11738902 | 0.76 | TSHR (0.39) | TSHRALDH1A1IDO1AGXTMAOB | |
| SCHEMBL8758260 | 0.75 | LMNA (0.51) | MAOBMAPTL3MBTL1OPRM1OPRD1 | |
| SCHEMBL28031391 | 0.75 | TSHR (0.35) | TSHRALDH1A1IDO1AGXTMAOB | |
| SCHEMBL1351516 | 0.75 | LMNA (0.51) | MAOBMAPTL3MBTL1OPRM1OPRD1 | |
| SCHEMBL7076809 | 0.75 | TSHR (0.46) | TSHRALDH1A1IDO1AGXTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513194-B1 | FUNCTIONALLY BRANCHED POLYETHER COPOLYMERS AND METHOD FOR THE PRODUCTION THEREOF | JOHANNES GUTENBERG UNIVERSITÄT MAINZ VERTRETEN DURCH DEN PRÄSIDENTEN (DE) | 2016-08-31 | — | — | EP | claimed |
| CN-112574058-B | Synthetic route of lacosamide | 珠海润都制药股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-0327455-B1 | ALKYL OR BENZYL ETHERS OF PHENOL, PROCESSES FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | DELALANDE S.A. (FR) | 1992-09-16 | — | — | EP | disclosed |
| US-4971995-A | INHIBITORS OF MONOAMINE OXIDASE, NEUROLOGICAL DISORDERS, AGING, MEMORY PROBLEMS, SCHIZOPHRENIA, PSYDHAESTHINIA, PARKINSON*S DISEASE | DELANDE S.A. (FR) | 1990-11-20 | — | — | US | disclosed |
| EP-0327455-A1 | Alkyl or benzyl ethers of phenol, processes for their preparation and their therapeutical use | DELALANDE S.A. (FR) | 1989-08-09 | — | — | EP | disclosed |