Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 5/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29783468 | 0.98 | SLC7A5 (0.56) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL76796 | 0.98 | SLC7A5 (0.56) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL700933 | 0.98 | SLC7A5 (0.56) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL196338 | 0.98 | SLC7A5 (0.56) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| Hydrochloric Acid SCHEMBL353346 | 0.95 | SLC7A5 (0.54) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| Hydrochloric Acid SCHEMBL76795 | 0.95 | SLC7A5 (0.54) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| Hydrochloric Acid SCHEMBL355415 | 0.95 | SLC7A5 (0.54) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| Methyl Alcohol SCHEMBL28477033 | 0.95 | SLC7A5 (0.54) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| Hydrochloric Acid SCHEMBL1532654 | 0.93 | SLC7A5 (0.52) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| Alanine SCHEMBL7256054 | 0.90 | SLC7A5 (0.59) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061236-B | Amino-acid ester bromination salt form chiral ionic liquid and preparation method thereof | 唐山师范学院 | 2016-09-28 | — | — | CN | disclosed |
| CN-105061236-A | Amino-acid ester bromide type chiral ionic liquid and preparation method thereof | UNIV TANGSHAN NORMAL | 2015-11-18 | — | — | CN | disclosed |