Hydrochloric Acid

Hydrochloric Acid

SCHEMBL76795

COC(=O)[C@@H](N)CC(C)C.Cl

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.54
ANPEP P15144 5/20 0.44
RNPEP Q9H4A4 2/20 0.44
DNPEP Q9ULA0 1/20 0.44
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
CA14 Q9ULX7 1/20 0.40
MME P08473 2/20 0.40
FOLH1 Q04609 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
LARS1 Q9P2J5 1/20 0.38
LAP3 P28838 2/20 0.37
ERAP1 Q9NZ08 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL355415 1.00 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Hydrochloric Acid SCHEMBL353346 1.00 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL76796 0.98 SLC7A5 (0.56) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL29783468 0.98 SLC7A5 (0.56) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL196338 0.98 SLC7A5 (0.56) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL700933 0.98 SLC7A5 (0.56) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Methyl Alcohol SCHEMBL28477033 0.95 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Bromide SCHEMBL28031435 0.95 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Alcohol SCHEMBL28297686 0.94 SLC7A5 (0.48) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Hydrochloric Acid SCHEMBL1532654 0.93 SLC7A5 (0.52) SLC7A5ANPEPRNPEPDNPEPSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504883-A Synthesis method of RNA monomer intermediate 2' -fluoro-nucleoside modifier 安徽信佰生物医药科技有限公司 2025-02-25 CN claimed
CN-119409588-A Caffeoyl amino acid methyl ester derivative and preparation method and application thereof 西北大学 2025-02-11 CN claimed
CN-119241617-A 2 '-Deoxy-2' -fluoro-N4-substituted cytidine compound, preparation method and application thereof 河南省科学院高新技术研究中心 2025-01-03 CN claimed
CN-114983852-B Anti-aging cosmetic with whitening and moisturizing effects and preparation method thereof 中科重生(雄安)生物科技有限公司 2024-10-01 CN claimed
CN-118662369-A Crease-resistant skin care composition containing organic nitrate and preparation method thereof 瑞思益特(江西)生物科技开发有限公司 2024-09-20 CN claimed
CN-118078964-B Recombinant human interferon ointment and its preparation method 长春生物制品研究所有限责任公司 2024-07-12 CN claimed
CN-118078964-A Recombinant human interferon ointment and its preparation method 长春生物制品研究所有限责任公司 2024-05-28 CN claimed
CN-118001199-A Anti-oxidation and skin tightening essence containing tri-factor tripeptide and preparation method thereof 中科润航健康科技有限公司 2024-05-10 CN claimed
CN-117946007-A Curcumin-amino acid methyl ester derivative and preparation method and application thereof 河北科技大学 2024-04-30 CN claimed
CN-117462561-A Minocycline-containing composition for treating acne and preparation method thereof 广州仁恒医药科技股份有限公司 2024-01-30 CN claimed
US-20100145070-A1 ANTI-CANCER COMPOUND AND MANUFACTURING METHOD THEREOF NATIONAL DEFENSE MEDICAL CENTER (TW) 2010-06-10 US claimed
EP-1155001-A4 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2003-05-28 EP claimed
US-6417195-B1 LIBRARIES AND COMBINATORIAL CHEMISTRY LION BIOSCIENCE AG (DE) 2002-07-09 US claimed
EP-1155001-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 2001-11-21 EP claimed
WO-2000050406-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2000-08-31 WO claimed
EP-0397652-B1 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID GENZYME CORP (US) 1996-06-05 EP claimed
EP-0397652-A4 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID 1991-04-03 EP claimed
EP-0397652-A1 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID. GENZYME CORP (US) 1990-11-22 EP claimed
US-4937270-A Water insoluble derivatives of hyaluronic acid GENZYME CORPORATION (US) 1990-06-26 US claimed
WO-1989002445-A1 WATER INSOLUBLE DERIVATIVES OF HYALURONIC ACID GENZYME CORPORATION (US) 1989-03-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145070-A1 ANTI-CANCER COMPOUND AND MANUFACTURING METHOD THEREOF DCK, DHPS, DHX15 SLC7A5 2015/4885ANPEP 1411/4885RNPEP 1599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.