Hydrochloric Acid

Hydrochloric Acid

SCHEMBL355415

COC(=O)C(N)CC(C)C.Cl

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.54
ANPEP P15144 5/20 0.44
RNPEP Q9H4A4 2/20 0.44
DNPEP Q9ULA0 1/20 0.44
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
CA14 Q9ULX7 1/20 0.40
MME P08473 2/20 0.40
FOLH1 Q04609 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
LARS1 Q9P2J5 1/20 0.38
LAP3 P28838 2/20 0.37
ERAP1 Q9NZ08 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL76795 1.00 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Hydrochloric Acid SCHEMBL353346 1.00 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL76796 0.98 SLC7A5 (0.56) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL29783468 0.98 SLC7A5 (0.56) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL196338 0.98 SLC7A5 (0.56) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL700933 0.98 SLC7A5 (0.56) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Methyl Alcohol SCHEMBL28477033 0.95 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Bromide SCHEMBL28031435 0.95 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Alcohol SCHEMBL28297686 0.94 SLC7A5 (0.48) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Hydrochloric Acid SCHEMBL1532654 0.93 SLC7A5 (0.52) SLC7A5ANPEPRNPEPDNPEPSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409588-A Caffeoyl amino acid methyl ester derivative and preparation method and application thereof 西北大学 2025-02-11 CN claimed
CN-117338752-A Food-grade targeted enteric composite embedding method 赛尔生命科学(东莞)有限公司 2024-01-05 CN claimed
CN-114478690-B Preparation method of 6, 6-dimethyl-3-azabicyclo [3.1.0] hexane derivative 新发药业有限公司 2024-01-02 CN claimed
CN-113912524-B Polypeptide compound containing sulfur amide and synthesis method thereof 华东师范大学 2023-12-01 CN claimed
CN-116970587-A Alpha-amino acid ester acyltransferase mutant, amino acid sequence and application thereof 大连医诺生物股份有限公司 2023-10-31 CN claimed
CN-114773393-B Compound, preparation method thereof and circularly polarized luminescent material containing compound 中国科学院化学研究所 2023-10-27 CN claimed
CN-113527399-B Ginsenoside CK derivative and application thereof in preparation of antitumor drugs 陕西巨子生物技术有限公司 2023-01-31 CN claimed
CN-114773393-A Compound, preparation method thereof and circular polarization luminescent material containing compound 中国科学院化学研究所 2022-07-22 CN claimed
CN-114453022-A Acid catalyst for reducing acid value of high-acid-value oil, preparation method, recovery method and application thereof 大连医诺生物股份有限公司 2022-05-10 CN claimed
CN-114344230-A Composition for inhibiting bacteria, removing mites and removing acnes, and preparation method and application thereof 广州美果生物科技有限公司 2022-04-15 CN claimed
CN-106117311-A Cyclic peptide compound and preparation method and application thereof 沈阳兴齐眼药股份有限公司 2016-11-16 CN claimed
CN-103981248-B A kind of leucic method of resolution of racemic SOUTHEAST UNIVERSITY (CN) 2016-03-16 CN claimed
CN-105343097-A Composition containing caffeine and application and manufacturing method of composition containing caffeine TIANJIN JIANLAIDE TECHNOLOGY CO LTD 2016-02-24 CN claimed
CN-105198789-A Substituted3-indole Bcl-2 protein inhibitor and preparation method and application thereof UNIV SHANDONG 2015-12-30 CN claimed
CN-103749939-B A kind of soybean protein isolate preparation method being rich in branched-chain amino acid NORTHEAST AGRICULTURAL UNIVERSITY (CN) 2015-10-21 CN claimed
CN-103981248-A Method for splitting racemic leucine UNIV SOUTHEAST 2014-08-13 CN claimed
CN-103923178-A Small peptide, synthesis method thereof, and applications of small peptide on enhancing immunity of livestock UNIV NANJING XIAOZHUANG 2014-07-16 CN claimed
CN-103613643-A Bioactive small peptide, synthesis method and use thereof as animal feed additive UNIV NANJING XIAOZHUANG 2014-03-05 CN claimed
CN-102382014-A Aminopeptidase N inhibitor, preparation method and application WEIFANG BOCHUANG INTERNAT BIOLOG MEDICAL RES INST 2012-03-21 CN claimed
US-20100145070-A1 ANTI-CANCER COMPOUND AND MANUFACTURING METHOD THEREOF NATIONAL DEFENSE MEDICAL CENTER (TW) 2010-06-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145070-A1 ANTI-CANCER COMPOUND AND MANUFACTURING METHOD THEREOF DCK, DHPS, DHX15 SLC7A5 2015/4885ANPEP 1411/4885RNPEP 1599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.