Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503154 | 0.85 | DRD1 (0.44) | DRD1PTGS1MEN1KMT2AROCK2 | |
| SCHEMBL824148 | 0.85 | KDM4E (0.46) | DRD1PTGS1MEN1KMT2AKCNK2 | |
| SCHEMBL27708876 | 0.85 | RXRA (0.44) | PTGS1MEN1KMT2ACYP2D6SMN1; SMN2 | |
| SCHEMBL29699116 | 0.81 | MEN1 (0.45) | DRD1PTGS1MEN1KMT2ACYP2D6 | |
| SCHEMBL16044648 | 0.81 | DRD1 (0.41) | DRD1PTGS1MEN1KMT2AKCNK2 | |
| SCHEMBL24588262 | 0.81 | DRD1 (0.41) | DRD1PTGS1MEN1KMT2ACYP2D6 | |
| SCHEMBL4230419 | 0.81 | DRD1 (0.41) | DRD1PTGS1MEN1KMT2AKCNK2 | |
| SCHEMBL16950312 | 0.81 | DRD1 (0.41) | DRD1PTGS1MEN1KMT2ACYP2D6 | |
| SCHEMBL15943226 | 0.81 | MEN1 (0.45) | DRD1PTGS1MEN1KMT2ACYP2D6 | |
| SCHEMBL19876580 | 0.81 | DRD1 (0.41) | DRD1PTGS1MEN1KMT2AKCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022116998-A1 | FUSED HETEROCYCLIC DERIVATIVES AS HBV INHIBITORS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-06-09 | — | — | WO | disclosed |
| CN-104870422-A | Novel amine derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |