SCHEMBL28503154

SCHEMBL28503154

FC(F)Oc1cccc(C(Br)Br)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.44
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
MAPT P10636 3/20 0.39
NPSR1 Q6W5P4 3/20 0.39
RAB9A P51151 3/20 0.39
LMNA P02545 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
TAS2R14 Q9NYV8 1/20 0.39
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GRM4 Q14833 2/20 0.38
MEP1B Q16820 1/20 0.38
ATM Q13315 1/20 0.37
DAO P14920 1/20 0.37
RXRA P19793 1/20 0.37
GRIN1 Q05586 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28031476 0.85 DRD1 (0.41) DRD1KMT2AMEN1MAPTNPSR1
SCHEMBL18920470 0.82 PTGS1 (0.45) DRD1KMT2AMEN1MAPTNPSR1
SCHEMBL6988479 0.80 DRD1 (0.49) DRD1KMT2AMEN1MAPTNPSR1
SCHEMBL3721185 0.80 RXRA (0.44) KMT2AMEN1RAB9ALMNAHTT
SCHEMBL824148 0.80 KDM4E (0.46) DRD1KMT2AMEN1MAPTNPSR1
SCHEMBL24588262 0.77 DRD1 (0.41) DRD1KMT2AMEN1MAPTNPSR1
SCHEMBL16950312 0.77 DRD1 (0.41) DRD1KMT2AMEN1MAPTNPSR1
SCHEMBL4230419 0.77 DRD1 (0.41) DRD1KMT2AMEN1MAPTNPSR1
SCHEMBL19876580 0.77 DRD1 (0.41) DRD1KMT2AMEN1MAPTNPSR1
SCHEMBL15943226 0.77 MEN1 (0.45) DRD1KMT2AMEN1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112041296-A Aminoacetamides containing benzo-oxy-alicyclic structure and use thereof 上海璃道医药科技有限公司 2020-12-04 CN disclosed