Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504622 | 0.84 | PDK2 (0.35) | PDK2S100A4AKR1A1AKR1B1PTPRC | |
| SCHEMBL19831170 | 0.84 | PDK2 (0.35) | PDK2S100A4AKR1A1AKR1B1PTPRC | |
| SCHEMBL20508944 | 0.82 | LMNA (0.34) | PDK2 | |
| SCHEMBL15430906 | 0.81 | PDK2 (0.42) | PDK2S100A4AKR1A1AKR1B1PTPRC | |
| SCHEMBL1115844 | 0.81 | PDK2 (0.36) | PDK2S100A4AKR1A1AKR1B1PTPRC | |
| SCHEMBL29514438 | 0.78 | PDK2 (0.41) | PDK2S100A4AKR1A1AKR1B1PTPRC | |
| SCHEMBL1086094 | 0.78 | PDK2 (0.41) | PDK2S100A4AKR1A1AKR1B1PTPRC | |
| SCHEMBL5502914 | 0.77 | PDK2 (0.43) | PDK2PTPRC | |
| SCHEMBL5653817 | 0.77 | PDK2 (0.43) | PDK2PTPRC | |
| SCHEMBL340410 | 0.76 | MMP9 (0.40) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040718-B2 | Hybrid host materials for electrophosphorescent devices | THE UNIVERSITY OF ROCHESTER (US) | 2015-05-26 | — | — | US | disclosed |
| WO-2010085676-A1 | HYBRID HOST MATERIALS FOR ELECTROPHOSPHORESCENT DEVICES | UNIVERSITY OF ROCHESTER (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | THE UNIVERSITY OF ROCHESTER | 2010-07-22 | — | — | US | disclosed |
| EP-2033979-A1 | Copolymer or polymer composition and polymer light-emitting device | Sumitomo Chemical Company, Limited (JP) | 2009-03-11 | — | — | EP | disclosed |
| EP-1323762-B1 | Copolymer or polymer composition and polymer light-emitting device | SUMITOMO CHEMICAL CO (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-6926973-B2 | Copolymer, polymer composition and polymer light-emitting device | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-09 | — | — | US | disclosed |
| US-20030143429-A1 | Copolymer, polymer composition and polymer light-emitting device | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-07-31 | — | — | US | disclosed |
| EP-1323762-A2 | Copolymer or polymer composition and polymer light-emitting device | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | SLC29A2, SLC43A3, SLC29A1 | PDK2 3091/4885S100A4 1238/4885AKR1A1 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.