Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030562 | 0.82 | HAO1 (0.45) | KDM4EKMT2ACYP1A2CYP2C19 | |
| SCHEMBL10970875 | 0.81 | TDP1 (0.52) | EGFRALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL19977428 | 0.75 | EGFR (0.50) | EGFRABCG2ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL6136728 | 0.74 | EGFR (0.52) | EGFRABCG2ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28035897 | 0.72 | KMT2A (0.47) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20704068 | 0.72 | MRGPRX4 (0.44) | EGFRMRGPRX4ABCG2ALDH1A1KMT2A | |
| SCHEMBL23319939 | 0.71 | HAO1 (0.41) | MRGPRX4KDM4EKMT2ACYP1A2MAPT | |
| SCHEMBL26195027 | 0.71 | ICAM1 (0.41) | EGFRMRGPRX4KDM4EALDH1A1KMT2A | |
| SCHEMBL8476094 | 0.70 | ALDH1A1 (0.51) | KDM4EALDH1A1KMT2A | |
| SCHEMBL5519221 | 0.70 | SRD5A2 (0.61) | MRGPRX4KDM4ECYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017166-A | Preparation method of 3-(3-bromine phenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOLOG TECHNOLOGY CO LTD | 2015-11-04 | — | — | CN | disclosed |
| CN-105017166-A | Preparation method of 3-(3-bromine phenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOLOG TECHNOLOGY CO LTD | 2015-11-04 | — | — | CN | disclosed |