Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030562 | 0.81 | HAO1 (0.45) | KMT2AHAO1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL2424045 | 0.79 | KMT2A (0.48) | KMT2AKDM4EASPHKDM8CYP3A4 | |
| SCHEMBL8343982 | 0.78 | CARM1 (0.52) | TRPA1CYP2C9CYP2C19 | |
| SCHEMBL2779361 | 0.78 | KMT2A (0.65) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28033079 | 0.78 | MAPT (0.49) | KMT2ATRPA1KDM4EASPHKDM8 | |
| SCHEMBL28033083 | 0.76 | KMT2A (0.44) | KMT2AHAO1TRPA1CYP3A4CYP1A2 | |
| SCHEMBL28033082 | 0.75 | CYP1A2 (0.43) | KMT2AHAO1TRPA1KDM4ECYP3A4 | |
| SCHEMBL15923438 | 0.74 | MAPT (0.55) | KMT2AHAO1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL30439979 | 0.73 | KDR (0.47) | TRPA1KDM4EASPHKDM8CYP3A4 | |
| SCHEMBL28031645 | 0.72 | EGFR (0.46) | KMT2AKDM4ECYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961690-A | Preparation method of 3-(4-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | claimed |
| CN-104961690-A | Preparation method of 3-(4-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |
| CN-104961690-A | Preparation method of 3-(4-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |
| CN-104961690-A | Preparation method of 3-(4-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |