Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | RORA | P35398 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13231765 | 0.97 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4ERORCFDFT1 | |
| SCHEMBL13231766 | 0.91 | KDM4E (0.40) | ALDH1A1HPGDKDM4ERORCFDFT1 | |
| SCHEMBL2800395 | 0.88 | KDM4E (0.50) | ALDH1A1HPGDKDM4ERORCFDFT1 | |
| SCHEMBL2798021 | 0.86 | KDM4E (0.51) | ALDH1A1HPGDKDM4ERORCFDFT1 | |
| SCHEMBL2801396 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ERORCFDFT1 | |
| SCHEMBL2801388 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4ERORCDNM1 | |
| SCHEMBL13264172 | 0.81 | KDM4E (0.37) | ALDH1A1HPGDKDM4ERORCFDFT1 | |
| SCHEMBL2799882 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ERORCDNM1 | |
| SCHEMBL2801070 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ERORCDNM1 | |
| SCHEMBL2800760 | 0.79 | KDM4E (0.50) | ALDH1A1HPGDKDM4ERORCFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040718-B2 | Hybrid host materials for electrophosphorescent devices | THE UNIVERSITY OF ROCHESTER (US) | 2015-05-26 | — | — | US | claimed |
| WO-2010085676-A1 | HYBRID HOST MATERIALS FOR ELECTROPHOSPHORESCENT DEVICES | UNIVERSITY OF ROCHESTER (US) | 2010-07-29 | — | — | WO | claimed |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | THE UNIVERSITY OF ROCHESTER | 2010-07-22 | — | — | US | claimed |
| US-9040718-B2 | Hybrid host materials for electrophosphorescent devices | THE UNIVERSITY OF ROCHESTER (US) | 2015-05-26 | — | — | US | disclosed |
| WO-2010085676-A1 | HYBRID HOST MATERIALS FOR ELECTROPHOSPHORESCENT DEVICES | UNIVERSITY OF ROCHESTER (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | THE UNIVERSITY OF ROCHESTER | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | SLC29A2, SLC43A3, SLC29A1 | ALDH1A1 2164/4885HPGD 3352/4885KDM4E 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.