Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799882 | 0.98 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EMEN1RAD52 | |
| SCHEMBL2803193 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EMEN1RAD52 | |
| SCHEMBL2801388 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EKMT2ATSPO | |
| SCHEMBL13231766 | 0.82 | KDM4E (0.40) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL2803197 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4ETSPODNM1 | |
| SCHEMBL2803166 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4ETSPOPTGER4 | |
| SCHEMBL2801681 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1RAD52 | |
| SCHEMBL13231765 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EPTGER4DNM1 | |
| SCHEMBL3848636 | 0.75 | KDM4E (0.63) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL2803154 | 0.74 | PDK2 (0.38) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040718-B2 | Hybrid host materials for electrophosphorescent devices | THE UNIVERSITY OF ROCHESTER (US) | 2015-05-26 | — | — | US | disclosed |
| WO-2010085676-A1 | HYBRID HOST MATERIALS FOR ELECTROPHOSPHORESCENT DEVICES | UNIVERSITY OF ROCHESTER (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | THE UNIVERSITY OF ROCHESTER | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | SLC29A2, SLC43A3, SLC29A1 | ALDH1A1 2164/4885HPGD 3352/4885KDM4E 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.