Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703905 | 0.89 | GRM1 (0.62) | GRM1LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL2229135 | 0.82 | ALDH1A1 (0.49) | GRM1LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL30098818 | 0.81 | GRM1 (0.47) | GRM1LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL2228761 | 0.81 | GRM1 (0.47) | GRM1LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL2283812 | 0.75 | NPC1 (0.54) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2227205 | 0.75 | NPC1 (0.51) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL28998070 | 0.74 | ACHE (0.63) | NPC1RAB9A | |
| SCHEMBL2633409 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL31544703 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10472947 | 0.74 | KDM4E (0.51) | GRM1LMNAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781919-B | As the amido acridine derivatives of the selective depressant of ubiquitin-specific protease 7 | HYBRIGENICS S.A. (FR) | 2016-01-20 | — | — | CN | disclosed |