SCHEMBL28032027

SCHEMBL28032027

CCCCCCCCCCCCCCCCc1c(C(=O)O)cc(C)cc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.53
PPARA Q07869 2/20 0.53
RARB P10826 3/20 0.51
PLK1 P53350 8/20 0.50
PLK3 Q9H4B4 2/20 0.50
PPARG P37231 1/20 0.49
RARA P10276 1/20 0.48
RARG P13631 1/20 0.48
HCAR2 Q8TDS4 1/20 0.45
GPR35 Q9HC97 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27639640 1.00 KAT8 (0.53) KAT8PPARARARBPLK1PLK3
SCHEMBL27607961 0.92 GABRP (0.46) KAT8PPARARARBPLK1PLK3
SCHEMBL9099516 0.87 KAT8 (0.55) KAT8PPARARARBPPARGRARA
SCHEMBL8861090 0.85 KAT8 (0.49) KAT8PPARARARBPLK1PPARG
SCHEMBL14989184 0.84 KAT8 (0.51) KAT8PPARARARBPLK1PPARG
SCHEMBL14989188 0.84 KAT8 (0.51) KAT8PPARARARBPLK1PPARG
SCHEMBL14989165 0.84 KAT8 (0.51) KAT8PPARARARBPLK1PPARG
SCHEMBL14989185 0.84 KAT8 (0.51) KAT8PPARARARBPLK1PPARG
SCHEMBL14989183 0.84 KAT8 (0.51) KAT8PPARARARBPLK1PPARG
SCHEMBL14989293 0.84 KAT8 (0.51) KAT8PPARARARBPLK1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104877127-A Eight-armed polyethylene glycol derivative, preparation method and related biological substance modified by derivative XIAMEN SINOPEG BIOTECH CO LTD 2015-09-02 CN disclosed