Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Grevillol SCHEMBL31345744 | 0.92 | KAT8 (0.59) | KAT8PPARAPTGS2RARBCYP3A4 | |
| SCHEMBL28032027 | 0.87 | KAT8 (0.53) | KAT8PPARARARBPPARGHCAR2 | |
| SCHEMBL27639640 | 0.87 | KAT8 (0.53) | KAT8PPARARARBPPARGHCAR2 | |
| SCHEMBL1547662 | 0.85 | TSHR (0.51) | CYP3A4 | |
| SCHEMBL39571 | 0.84 | KAT8 (0.50) | KAT8PPARACYP3A4PPARGHCAR2 | |
| SCHEMBL8861090 | 0.84 | KAT8 (0.49) | KAT8PPARARARBPPARGRARA | |
| SCHEMBL14989165 | 0.82 | KAT8 (0.51) | KAT8PPARARARBPPARGHCAR2 | |
| SCHEMBL14989183 | 0.82 | KAT8 (0.51) | KAT8PPARARARBPPARGHCAR2 | |
| SCHEMBL14989185 | 0.82 | KAT8 (0.51) | KAT8PPARARARBPPARGHCAR2 | |
| SCHEMBL14989184 | 0.82 | KAT8 (0.51) | KAT8PPARARARBPPARGHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484585-A | CONTAIN NONIONIC, CATIONIC, ANIONIC, ZWITTERIONIC SURFACTANTS, EXCIPIENTS, AND WATER; X-RAY CONTRAST AND COMPUTED TOMOGRAPHY; MEDICAL DIAGNOSIS | STERLING-WINTHROP INC. (US) | 1996-01-16 | — | — | US | disclosed |
| US-5385720-A | X-ray radiology and computer tomography; uniform coating of the soft tissues; medical diagnosis | STERLING WINTHROP INC. (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0614669-A2 | Compositions of iodobenzoic acid derivatives in filmforming materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-09-14 | — | — | EP | disclosed |
| EP-0614668-A2 | Composition of iodobenzoic acid derivatives for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-09-14 | — | — | EP | disclosed |
| US-5344638-A | Contrast agents for medicine | STERLING WINTHROP INC. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5312616-A | Radiopaque coating for x-ray examination | STERLING WINTHROP INC. (US) | 1994-05-17 | — | — | US | disclosed |