SCHEMBL28032097

SCHEMBL28032097

CCc1ccc(Oc2ccc(CC)cc2C(=O)O)c(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CFD P00746 2/20 0.56
ALDH1A1 P00352 1/20 0.47
METAP2 P50579 2/20 0.47
FOLH1 Q04609 2/20 0.46
PTPN1 P18031 1/20 0.46
PTPN6 P29350 1/20 0.46
PTPN11 Q06124 1/20 0.46
KMT2A Q03164 1/20 0.46
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
KAT8 Q9H7Z6 2/20 0.45
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
MRGPRX4 Q96LA9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384685 0.87 MRGPRX4 (0.57) CFDALDH1A1METAP2KMT2APPARG
SCHEMBL8471711 0.86 KMT2A (0.60) CFDALDH1A1FOLH1PTPN1PTPN6
SCHEMBL28032082 0.85 PPARA (0.53) CFDALDH1A1METAP2KMT2APPARG
SCHEMBL27761993 0.85 PTPN11 (0.60) CFDFOLH1PTPN1PTPN6PTPN11
SCHEMBL10592193 0.83 CFD (0.50) CFDALDH1A1METAP2FOLH1PTPN1
SCHEMBL11564248 0.83 CFD (0.58) CFDALDH1A1METAP2FOLH1KMT2A
SCHEMBL27374195 0.82 PTPN11 (0.68) ALDH1A1PTPN1PTPN6PTPN11KMT2A
SCHEMBL9501936 0.82 PTPN11 (0.68) ALDH1A1PTPN1PTPN6PTPN11KMT2A
SCHEMBL13493882 0.82 CFD (0.49) CFDALDH1A1METAP2FOLH1PTPN1
SCHEMBL28032017 0.81 CFD (0.51) CFDALDH1A1FOLH1PTPN1PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104968704-B Process for producing polyarylate 三菱瓦斯化学株式会社 2016-12-14 CN disclosed
CN-104968704-A Process for producing polyarylate MITSUBISHI GAS CHEMICAL CO 2015-10-07 CN disclosed