SCHEMBL28032082

SCHEMBL28032082

CCc1ccc(C(=O)O)c(Oc2cc(CC)ccc2C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.53
PPARG P37231 1/20 0.53
ALDH1A1 P00352 3/20 0.47
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CFD P00746 1/20 0.44
METAP2 P50579 2/20 0.43
HTT P42858 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
PKM P14618 1/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
KMT2A Q03164 1/20 0.42
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8650713 0.87 PPARA (0.51) PPARAPPARGALDH1A1RAB9ASMN1; SMN2
SCHEMBL5501065 0.87 PPARG (0.68) PPARAPPARGALDH1A1SMN1; SMN2HTT
SCHEMBL7791924 0.86 TSHR (0.51) PPARAPPARGALDH1A1KDM4EHPGD
SCHEMBL11427902 0.85 RXRA (0.47) PPARAPPARGALDH1A1HTTPKM
SCHEMBL28032097 0.85 CFD (0.56) PPARAPPARGALDH1A1CFDMETAP2
SCHEMBL27761412 0.83 PPARA (0.58) PPARAPPARGKDM4EMEN1KMT2A
SCHEMBL27741361 0.83 ALDH1A1 (0.51) PPARAPPARGALDH1A1
SCHEMBL13836988 0.83 PPARA (0.48) PPARAPPARGALDH1A1RAB9ASMN1; SMN2
SCHEMBL14273071 0.83 PTGDR2 (0.51) PPARAPPARGALDH1A1SMN1; SMN2HTT
SCHEMBL28032020 0.81 PPARG (0.45) PPARAPPARGALDH1A1CFDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104968704-B Process for producing polyarylate 三菱瓦斯化学株式会社 2016-12-14 CN disclosed
CN-104968704-A Process for producing polyarylate MITSUBISHI GAS CHEMICAL CO 2015-10-07 CN disclosed