Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8838566 | 0.98 | DRD3 (0.44) | DRD3SLC6A4SLC6A2SLC6A3HSD11B1 | |
| SCHEMBL28611137 | 0.95 | DRD3 (0.41) | DRD3SLC6A4SLC6A2SLC6A3HSD11B1 | |
| SCHEMBL776247 | 0.82 | PSEN1 (0.42) | SLC6A4SLC6A2SLC6A3PSEN1PSEN2 | |
| SCHEMBL778919 | 0.80 | GAA (0.42) | DRD3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL776248 | 0.79 | AKR1C1 (0.43) | SLC6A4SLC6A2SLC6A3PSEN1PSEN2 | |
| SCHEMBL18231167 | 0.77 | HSD11B1 (0.39) | DRD3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL778920 | 0.77 | AKR1C1 (0.44) | DRD3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15043695 | 0.75 | OPRM1 (0.58) | DRD3SLC6A4SLC6A2SLC6A3DPP4 | |
| SCHEMBL27854939 | 0.75 | CYP19A1 (0.39) | — | |
| SCHEMBL791817 | 0.73 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918942-A | Pyrimidone derivatives and their use for treating, ameliorating or preventing viral diseases | SAVIRA PHARMACEUTICALS GMBH | 2015-09-16 | — | — | CN | disclosed |