Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15501825 | 0.90 | LMNA (0.58) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL15899084 | 0.85 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL10805614 | 0.85 | LMNA (0.62) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL13430902 | 0.83 | GAA (0.50) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL28853887 | 0.83 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL2035293 | 0.82 | LMNA (0.69) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL29482311 | 0.80 | LMNA (0.67) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL1377760 | 0.80 | LMNA (0.67) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL30657703 | 0.80 | LMNA (0.67) | LMNASMN1; SMN2POLBGAAMAPK1 | |
| SCHEMBL1070126 | 0.80 | LMNA (0.67) | LMNASMN1; SMN2POLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926871-A | O,O-dialkyl-alpha-[3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formyl]alkyl methylphosphonate derivative as well as preparation method and application thereof | XIAN MODERN CHEMISTRY RES INST | 2015-09-23 | — | — | CN | disclosed |