SCHEMBL30657703

SCHEMBL30657703

O=P(Cl)(Oc1ccccc1Cl)Oc1ccccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
MAPK1 P28482 1/20 0.46
PKM P14618 2/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
PTK2B Q14289 1/20 0.42
HPGD P15428 3/20 0.40
TSHR P16473 2/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CXCL8 P10145 1/20 0.38
RAB9A P51151 1/20 0.38
HDAC6 Q9UBN7 1/20 0.37
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
TP53 P04637 1/20 0.36
HTT P42858 1/20 0.36
SENP2 Q9HC62 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070126 1.00 LMNA (0.67) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL27626350 0.90 LMNA (0.60) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL13467926 0.88 LMNA (0.58) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL1377760 0.86 LMNA (0.67) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL29482311 0.86 LMNA (0.67) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL11791487 0.86 LMNA (0.51) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL11795872 0.84 LMNA (0.50) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL2035293 0.84 LMNA (0.69) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL13467877 0.83 SMN1; SMN2 (0.53) LMNASMN1; SMN2MAPK1PKMPOLB
SCHEMBL9492467 0.83 SMN1; SMN2 (0.62) LMNASMN1; SMN2MAPK1PKMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024658-A Phospholipid terminal functionalized rare earth isoprene rubber and preparation method and application thereof 海南天然橡胶产业集团股份有限公司 2023-11-10 CN disclosed