Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27525479 | 0.89 | KMO (0.53) | TSHRDHODHERN1KMOERCC5 | |
| SCHEMBL492196 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL5043231 | 0.76 | — | — | |
| SCHEMBL27363689 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28741632 | 0.76 | — | — | |
| Urea SCHEMBL12500731 | 0.73 | KMO (0.52) | DHODHKMOCA12CA2CA9 | |
| SCHEMBL28427704 | 0.73 | DHODH (0.44) | DHODHKMOCA12CA2CA9 | |
| SCHEMBL8779987 | 0.72 | ERCC5 (0.61) | KMOALDH1A1GAAMAPTPRSS1 | |
| Acetamide SCHEMBL1259199 | 0.69 | DHODH (0.48) | DHODHKMOCA12CA2CA9 | |
| SCHEMBL21358330 | 0.69 | TSHR (0.41) | TSHRERN1KMOCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104845926-A | Gene knockout escherichia coli beneficial to recombinant protein extracellular secretion and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2015-08-19 | — | — | CN | disclosed |