Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GPR3 | P46089 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18663455 | 0.91 | KDM4E (0.46) | KDM4EGPR3CDC25BNR4A1NR4A2 | |
| SCHEMBL5358558 | 0.89 | KDM4E (0.50) | KDM4EGPR3CDC25BNR4A1NR4A2 | |
| SCHEMBL5358564 | 0.89 | NR4A1 (0.53) | KDM4EGPR3CDC25BNR4A1NR4A2 | |
| SCHEMBL8230482 | 0.87 | PIM1 (0.50) | KDM4EGPR3PIM1ALDH1A1MEN1 | |
| SCHEMBL3862098 | 0.87 | LIG1 (0.46) | KDM4EGPR3MGAMALDH1A1HPGD | |
| SCHEMBL27546968 | 0.84 | KDM4E (0.46) | KDM4EGPR3NR4A1NR4A2NR4A3 | |
| SCHEMBL27656146 | 0.82 | KDM4E (0.44) | KDM4EGPR3CDC25BNR4A1NR4A2 | |
| SCHEMBL27656141 | 0.82 | KDM4E (0.44) | KDM4EGPR3CDC25BNR4A1NR4A2 | |
| SCHEMBL30075099 | 0.82 | KDM4E (0.50) | KDM4EGPR3CDC25BNR4A1NR4A2 | |
| SCHEMBL29598792 | 0.77 | KDM4E (0.57) | KDM4EGPR3ALDH1A1HDAC8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854635-A | Synthesis method of phenanthridine-6 (5H) -ketone compound | 安徽中烟工业有限责任公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116854635-A | Synthesis method of phenanthridine-6 (5H) -ketone compound | 安徽中烟工业有限责任公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-108191834-B | Preparation method of benzo-fused N-heterocyclic compound | 中山大学 | 2020-10-16 | — | — | CN | disclosed |
| CN-110698430-A | Thiaphenanthrone derivative, method for synthesizing the same, and electronic device containing the same | 苏州久显新材料有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-110698430-A | Thiaphenanthrone derivative, method for synthesizing the same, and electronic device containing the same | 苏州久显新材料有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-110256346-A | Phenanthridines ketone compounds and preparation method and application with BRD4 albumen inhibiting effect | 浙江省医学科学院 | 2019-09-20 | — | — | CN | disclosed |
| CN-110256346-A | Phenanthridines ketone compounds and preparation method and application with BRD4 albumen inhibiting effect | 浙江省医学科学院 | 2019-09-20 | — | — | CN | disclosed |
| CN-109320497-A | A method of phenanthridines ketone compounds are prepared by copper compound induction | 广州大学 | 2019-02-12 | — | — | CN | disclosed |
| CN-108948029-A | Phenanthridinone derivative, and synthesis method and anti-tumor application thereof | 华中科技大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-108948029-A | Phenanthridinone derivative, and synthesis method and anti-tumor application thereof | 华中科技大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-108191834-A | A kind of preparation method of benzo-fused N- heterocyclic compounds | 中山大学 | 2018-06-22 | — | — | CN | disclosed |
| CN-104926723-B | Synthetic method of phenanthridine ketone compounds | 洛阳师范学院 | 2017-04-19 | — | — | CN | disclosed |
| CN-104926723-B | Synthetic method of phenanthridine ketone compounds | 洛阳师范学院 | 2017-04-19 | — | — | CN | disclosed |
| CN-104926723-B | Synthetic method of phenanthridine ketone compounds | 洛阳师范学院 | 2017-04-19 | — | — | CN | disclosed |
| CN-104926723-A | Synthetic method of phenanthridine ketone compounds | UNIV LUOYANG NORMAL | 2015-09-23 | — | — | CN | disclosed |
| CN-104926723-A | Synthetic method of phenanthridine ketone compounds | UNIV LUOYANG NORMAL | 2015-09-23 | — | — | CN | disclosed |