Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28032446

C1CCOC1.ClCc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
GAA P10253 2/20 0.51
MAOB P27338 4/20 0.50
BCHE P06276 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2C19 P33261 1/20 0.50
PTGS2 P35354 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HIF1A Q16665 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HRH3 Q9Y5N1 2/20 0.49
FFAR1 O14842 1/20 0.49
FFAR4 Q5NUL3 1/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAOA P21397 2/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703 0.87 LMNA (0.64) GAAMAOBBCHELMNACYP1A2
SCHEMBL9571885 0.85 LMNA (0.62) GAAMAOBBCHELMNACYP1A2
(Chloromethyl)Benzene SCHEMBL27762297 0.83 FKBP1A (0.41) KMT2ALMNASMN1; SMN2HTTMEN1
Tetrahydrofuran SCHEMBL29117380 0.83 MRGPRX4 (0.52) KMT2AGAAMAOBBCHELMNA
(Chloromethyl)Benzene SCHEMBL9002178 0.81 FKBP1A (0.40) KMT2ALMNARAB9ASMN1; SMN2MAPT
SCHEMBL6157815 0.81 APP (0.64) KMT2AGAAMAOBBCHELMNA
SCHEMBL23440397 0.79 LMNA (0.59) GAAMAOBBCHELMNACYP1A2
SCHEMBL25297779 0.78 LMNA (0.53) KMT2AGAAMAOBBCHELMNA
Benzylphenylether SCHEMBL28330386 0.77 LMNA (0.61) KMT2AGAAMAOBBCHELMNA
SCHEMBL10609652 0.75 LMNA (0.75) GAAMAOBBCHELMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104844448-A Synthetic method of Dl - salvianic acid XIAMEN SHENGJIANDA BIOTECH CO LTD 2015-08-19 CN disclosed