SCHEMBL28032475

SCHEMBL28032475

C=Cc1cccc(C)c1CC(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 5/20 0.37
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
NR3C1 P04150 1/20 0.31
SCN4A P35499 3/20 0.31
MAOA P21397 2/20 0.31
LMNA P02545 2/20 0.31
SCN1A P35498 2/20 0.31
SCN5A Q14524 2/20 0.31
SCN9A Q15858 2/20 0.31
MAOB P27338 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
NFKB1 P19838 1/20 0.31
KCNK3 O14649 1/20 0.31
CACNA1F O60840 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8120378 0.83 CXCR5 (0.35) CXCR5GABRA1GABRB2ALDH1A1TSHR
SCHEMBL4911892 0.81 GABRA1 (0.47) GABRA1GABRB2ALDH1A1
SCHEMBL29533387 0.80 GABRA1 (0.41) GABRA1GABRB2ALDH1A1TSHRTDP1
SCHEMBL8387578 0.80 GABRA1 (0.44) CXCR5GABRA1GABRB2ALDH1A1TSHR
SCHEMBL9310181 0.79 ALDH1A1 (0.35) ALDH1A1TSHRNR3C1CYP1A2TP53
SCHEMBL29700800 0.79 ALDH1A1 (0.35) ALDH1A1TSHRNR3C1CYP1A2TP53
SCHEMBL14100533 0.77 ALDH1A1 (0.34) ALDH1A1TSHRSCN4ACYP1A2TP53
SCHEMBL20305958 0.77 GABRA1 (0.36) GABRA1ALDH1A1TSHRCYP1A2TP53
SCHEMBL28165934 0.77 MAPT (0.37) GABRA1GABRB2ALDH1A1TSHRNR3C1
SCHEMBL9413121 0.77 ALDH1A1 (0.39) ALDH1A1TSHRCYP1A2TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061703-A Anion exchange block copolymers, their manufacture and their use KRATON POLYMERS US LLC 2015-11-18 CN disclosed
CN-104936990-A Anion exchange block copolymers, their manufacture and use KRATON POLYMERS US LLC 2015-09-23 CN disclosed