Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786752 | 1.00 | THRA (0.46) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL1031286 | 1.00 | THRA (0.46) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL12802122 | 1.00 | THRA (0.46) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL5988777 | 0.98 | THRB (0.45) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL12802043 | 0.93 | THRB (0.44) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL15874933 | 0.87 | TLR8 (0.48) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL12802342 | 0.87 | TLR8 (0.48) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL15874748 | 0.87 | TLR8 (0.48) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL10532923 | 0.86 | THRB (0.49) | THRATHRBMEN1KMT2ATLR8 | |
| SCHEMBL10744390 | 0.86 | THRB (0.49) | THRATHRBMEN1KMT2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105273204-A | Block Copolymers, Their Manufacture And Their Use | KRATON POLYMERS US LLC | 2016-01-27 | — | — | CN | disclosed |
| CN-105061703-A | Anion exchange block copolymers, their manufacture and their use | KRATON POLYMERS US LLC | 2015-11-18 | — | — | CN | disclosed |
| CN-104936990-A | Anion exchange block copolymers, their manufacture and use | KRATON POLYMERS US LLC | 2015-09-23 | — | — | CN | disclosed |