Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 4/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444118 | 0.84 | ENPP2 (0.71) | ENPP2AHRNR4A2F7LTA4H | |
| SCHEMBL5940 | 0.84 | ENPP2 (0.71) | ENPP2AHRNR4A2F7LTA4H | |
| SCHEMBL31333 | 0.80 | TTR (0.55) | ENPP2NPSR1TTREGFR | |
| SCHEMBL1248842 | 0.70 | GPR84 (0.69) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL1196529 | 0.70 | GPR84 (0.69) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL30593539 | 0.70 | GPR84 (0.69) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL29419532 | 0.70 | ENPP2 (1.00) | ENPP2AHRGPR84USP2GAA | |
| SCHEMBL6091 | 0.70 | ENPP2 (1.00) | ENPP2AHRGPR84USP2GAA | |
| SCHEMBL2407140 | 0.69 | ORAI1 (0.46) | ENPP2NPSR1TTREGFR | |
| SCHEMBL30587351 | 0.67 | AHR (1.00) | AHRNR4A2F7LTA4HF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884059-A | Mixed lineage kinase inhibitors for hiv/aids therapies | UNIV ROCHESTER | 2015-09-02 | — | — | CN | disclosed |