Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377437 | 1.00 | TSHR (0.52) | TSHRSLC1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL4744296 | 0.87 | TSHR (0.48) | TSHRSLC1A1 | |
| SCHEMBL667017 | 0.87 | TSHR (0.48) | TSHRSLC1A1 | |
| SCHEMBL5749928 | 0.87 | TSHR (0.48) | TSHRSLC1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL7925338 | 0.85 | L3MBTL1 (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL6654471 | 0.85 | L3MBTL1 (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL10386766 | 0.84 | L3MBTL1 (0.61) | TSHRL3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL5313852 | 0.83 | — | — | |
| SCHEMBL28243 | 0.83 | TSHR (0.50) | TSHRL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL5750324 | 0.82 | TSHR (0.52) | TSHRSLC1A1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037363-A | Novel synthetic method for entecavir compound | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-11-11 | — | — | CN | claimed |
| CN-118063463-A | Preparation method of entecavir | 苏州科技大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-109593090-A | A kind of synthetic method of Entecavir | 连云港贵科药业有限公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-105037363-B | A kind of entecavir compound prepared novel synthesis | 山东罗欣药业集团股份有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105037363-A | Novel synthetic method for entecavir compound | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-11-11 | — | — | CN | disclosed |
| CN-105037363-A | Novel synthetic method for entecavir compound | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-11-11 | — | — | CN | disclosed |