SCHEMBL28032949

SCHEMBL28032949

c1csc(-c2ccc(Nc3ccc(-c4cccs4)cc3)cc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.55
CYP17A1 P05093 1/20 0.48
CYP11B1 P15538 1/20 0.48
CYP11B2 P19099 1/20 0.48
KCNH2 Q12809 1/20 0.48
HDAC2 Q92769 1/20 0.46
ALK Q9UM73 1/20 0.45
CYP2E1 P05181 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2A6 P11509 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2B6 P20813 1/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
ALDH1A1 P00352 4/20 0.45
MAPT P10636 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17618198 0.94 ALK (0.52) LTA4HCYP17A1CYP11B1CYP11B2KCNH2
SCHEMBL28402564 0.86 HDAC2 (0.51) LTA4HCYP17A1CYP11B1CYP11B2KCNH2
SCHEMBL338810 0.85 LTA4H (0.70) LTA4HCYP17A1CYP11B1CYP11B2KCNH2
SCHEMBL14707941 0.83 LTA4H (0.53) LTA4HCYP17A1CYP11B1CYP11B2HDAC2
SCHEMBL7455134 0.83 LTA4H (0.67) LTA4HCYP17A1CYP11B1CYP11B2KCNH2
SCHEMBL7294764 0.83 LTA4H (0.52) LTA4HCYP17A1CYP11B1CYP11B2KCNH2
SCHEMBL12521460 0.83 LTA4H (0.52) LTA4HCYP17A1CYP11B1CYP11B2KCNH2
SCHEMBL1464252 0.80
SCHEMBL15400052 0.79 ALK (0.48) LTA4HCYP17A1CYP11B1CYP11B2HDAC2
SCHEMBL27709556 0.78 CYP3A4 (0.60) LTA4HCYP17A1CYP11B1CYP11B2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104844562-B A kind of many thienyl triphenylamine compounds and preparation method and application 南京信息工程大学 2017-07-11 CN claimed
CN-104844562-A Polythienyl triphenylamine compounds, and preparation method and application thereof UNIV NANJING INF SCI & TECH 2015-08-19 CN claimed
CN-104844562-B A kind of many thienyl triphenylamine compounds and preparation method and application 南京信息工程大学 2017-07-11 CN disclosed
CN-104844562-A Polythienyl triphenylamine compounds, and preparation method and application thereof UNIV NANJING INF SCI & TECH 2015-08-19 CN disclosed