Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698218 | 0.74 | ALOX5 (0.53) | POLBALOX5KDM4EMEN1ALDH1A1 | |
| SCHEMBL25704818 | 0.71 | ALOX5 (0.34) | ALOX5HTTCHRM3 | |
| SCHEMBL19968938 | 0.70 | KMT2A (0.39) | NPC1RAB9APOLBHSP90AA1ALOX5 | |
| SCHEMBL6704014 | 0.69 | ALOX5 (0.44) | POLBALOX5MEN1ALDH1A1KMT2A | |
| SCHEMBL29360424 | 0.68 | ALOX5 (0.44) | NPC1RAB9APOLBALOX5HTT | |
| SCHEMBL47009 | 0.68 | ALOX5 (0.44) | NPC1RAB9APOLBALOX5HTT | |
| SCHEMBL25848908 | 0.68 | KDM4E (0.37) | POLBHTTKDM4EMEN1LMNA | |
| SCHEMBL24139397 | 0.68 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL27630608 | 0.66 | AHR (0.33) | NPC1RAB9APOLBALOX5HTT | |
| SCHEMBL23696795 | 0.66 | AHR (0.50) | ALOX5LMNACHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892580-A | Novel benzimidazole-pyrilamine derivative and application thereof | PENG KUAI | 2015-09-09 | — | — | CN | disclosed |