SCHEMBL6704014

SCHEMBL6704014

CC1(C)c2ccccc2Oc2ccc(C(=O)O)c(C(=O)O)c21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 7/20 0.44
CYP2C9 P11712 2/20 0.38
CDC25A P30304 1/20 0.34
CDC25B P30305 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MYC P01106 1/20 0.33
AKR1C3 P42330 1/20 0.33
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
CASP6 P55212 1/20 0.32
GAA P10253 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6698218 0.85 ALOX5 (0.53) ALOX5CYP2C9HSD17B10MYCAKR1C3
SCHEMBL87485 0.73 CYP2C9 (0.45) ALOX5CYP2C9CDC25ACDC25BHSD17B10
SCHEMBL25704818 0.73 ALOX5 (0.34) ALOX5CHRM3
SCHEMBL27630608 0.72 AHR (0.33) ALOX5KMT2AMEN1POLBCHRM3
SCHEMBL21436917 0.71 ALOX5 (0.36) ALOX5CYP2C9CDC25ACDC25BHSD17B10
SCHEMBL31125706 0.70 DRD1 (0.33) ALOX5CHRM3
Biphenyl SCHEMBL28058633 0.70 BACE1 (0.33) CHRM3
SCHEMBL29360424 0.70 ALOX5 (0.44) ALOX5KMT2AMEN1POLBCHRM3
SCHEMBL47009 0.70 ALOX5 (0.44) ALOX5KMT2AMEN1POLBCHRM3
SCHEMBL28032975 0.69 NPC1 (0.43) ALOX5RARARARBRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004244381-A METHOD FOR PRODUCING 9,9-DIMETHYLXANTHENE DICARBOXYLIC ACID SEIMI CHEM CO LTD 2004-09-02 JP disclosed