Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864843 | 0.86 | ESR2 (0.43) | SLC6A3SLC6A4ESR2LMNANPSR1 | |
| SCHEMBL29635938 | 0.86 | ESR2 (0.43) | SLC6A3SLC6A4ESR2LMNANPSR1 | |
| SCHEMBL31332791 | 0.83 | SLC6A3 (0.42) | SLC6A3SLC6A4TSHR | |
| SCHEMBL27593184 | 0.79 | MAPT (0.33) | SLC6A3TSHREPHX2 | |
| SCHEMBL3703756 | 0.74 | ESR2 (0.42) | ESR2TSHRNPSR1 | |
| SCHEMBL3703757 | 0.74 | ESR2 (0.42) | ESR2TSHRNPSR1 | |
| SCHEMBL22552682 | 0.72 | TSHR (0.48) | SLC6A3SLC6A4TSHR | |
| SCHEMBL20819995 | 0.72 | TSHR (0.48) | SLC6A3SLC6A4TSHR | |
| SCHEMBL20819997 | 0.72 | TSHR (0.48) | SLC6A3SLC6A4TSHR | |
| SCHEMBL27797705 | 0.71 | EPHX2 (0.38) | SLC6A3SLC6A4EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105440540-A | INTERLAYER FOR ELECTRONIC DEVICES | MERCK PATENT GMBH | 2016-03-30 | — | — | CN | disclosed |
| CN-105038069-A | GATE INSULATOR LAYER FOR ELECTRONIC DEVICES | MERCK PATENT GMBH | 2015-11-11 | — | — | CN | disclosed |
| CN-104877292-A | Gate Insulator Layer For Organic Electronic Devices | PROMERUS LLC | 2015-09-02 | — | — | CN | disclosed |