Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938008 | 0.77 | TP53 (0.36) | TSHR | |
| SCHEMBL5549439 | 0.77 | TP53 (0.36) | TSHR | |
| SCHEMBL11490831 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL25764373 | 0.74 | — | — | |
| SCHEMBL10254715 | 0.71 | SMN1; SMN2 (0.38) | TSHR | |
| SCHEMBL1970742 | 0.71 | SMN1; SMN2 (0.38) | TSHR | |
| SCHEMBL8675050 | 0.71 | TP53 (0.44) | LMNAALOX15BLMPMP22 | |
| SCHEMBL22893306 | 0.70 | — | — | |
| SCHEMBL19891782 | 0.70 | EPHX1 (0.38) | LMNAALOX15BLMPMP22 | |
| SCHEMBL819540 | 0.69 | ALDH1A1 (0.41) | LMNAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102659643-B | A kind of by α, beta-unsaturated acyl amine prepares the method replacing Homotaurine | BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) | 2015-10-14 | — | — | CN | disclosed |