Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 4/20 | 0.34 |
| ▸ | METAP1 | P53582 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113315 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL6171365 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL18113118 | 0.79 | CHRNB2 (0.34) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL1970742 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1KMT2ACYP2C9CYP2C19TSHR | |
| SCHEMBL18113151 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL11063755 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL18113109 | 0.77 | LMNA (0.32) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL18113185 | 0.77 | METAP2 (0.33) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL1977310 | 0.77 | TSHR (0.42) | TSHR | |
| SCHEMBL19318891 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10ALOX15MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334201-B1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO PERFUMERY CO LTD (JP) | 2016-07-27 | — | — | EP | claimed |
| US-20110256071-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-10-20 | — | — | US | claimed |
| EP-2334201-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | Takasago International Corporation (JP) | 2011-06-22 | — | — | EP | claimed |
| WO-2010042938-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-04-15 | — | — | WO | claimed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| EP-2334201-B1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO PERFUMERY CO LTD (JP) | 2016-07-27 | — | — | EP | disclosed |
| US-8536364-B2 | Method for producing sulfur-containing carboxylic acid esters | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-09-17 | — | — | US | disclosed |
| US-8445051-B2 | Thiol-containing fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-05-21 | — | — | US | disclosed |
| EP-2452933-A1 | Method for producing sulfur-containing carboxylic acid esters | Takasago International Corporation (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-20110282089-A1 | METHOD FOR PRODUCING SULFUR-CONTAINING CARBOXYLIC ACID ESTERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-11-17 | — | — | US | disclosed |
| US-20110256071-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-2334201-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | Takasago International Corporation (JP) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010042938-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256071-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAS1R1, TAS2R1, TAS2R5 | ALDH1A1 29/4885LMNA 4318/4885HSD17B10 383/4885 |
| US-20110282089-A1 | METHOD FOR PRODUCING SULFUR-CONTAINING CARBOXYLIC ACID ESTERS | CBR3, ALDH18A1, TAS2R3 | ALDH1A1 37/4885LMNA 4844/4885HSD17B10 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.