Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.40 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869989 | 0.92 | CA2 (0.63) | CA2CA9CA1ALDH1A1TSHR | |
| SCHEMBL332355 | 0.79 | CA2 (0.63) | CA2CA9CA1ALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL11103734 | 0.79 | TSHR (0.68) | CA2CA9CA1ALDH1A1LMNA | |
| Styrene SCHEMBL17157473 | 0.79 | CA2 (0.49) | CA2CA9CA1ALDH1A1LMNA | |
| SCHEMBL27464853 | 0.78 | CA2 (0.57) | CA2CA9CA1ALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL28824537 | 0.78 | CA2 (0.61) | CA2CA9CA1ALDH1A1LMNA | |
| Water SCHEMBL11053215 | 0.78 | CA2 (0.61) | CA2CA9CA1ALDH1A1LMNA | |
| Hydrogen Sulfide SCHEMBL12483354 | 0.78 | CA2 (0.61) | CA2CA9CA1ALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL28824538 | 0.78 | CA2 (0.61) | CA2CA9CA1ALDH1A1LMNA | |
| SCHEMBL28152426 | 0.78 | CA2 (0.61) | CA2CA9CA1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105074571-B | Use the method for thiosulfate polymer chelated mineral | 伊斯曼柯达公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-106688050-B | The device of dielectric layer with band polymer containing thiosulfate | 伊斯曼柯达公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-106688050-A | Devices having dielectric layers with thiosulfate-containing polymers | 伊斯曼柯达公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-105073200-A | Thiosulfate polymer compositions and articles | EASTMAN KODAK CO | 2015-11-18 | — | — | CN | disclosed |
| CN-105074571-A | Method of sequestering metals using thiosulfate polymers | EASTMAN KODAK CO | 2015-11-18 | — | — | CN | disclosed |