Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.41 |
| ▸ | LPL | P06858 | 7/20 | 0.41 |
| ▸ | F11 | P03951 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258023 | 0.88 | LPL (0.39) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL13198632 | 0.86 | LIPG (0.57) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL16865630 | 0.86 | LIPG (0.51) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL18953871 | 0.85 | LIPG (0.41) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL12533689 | 0.83 | LPL (0.40) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL441381 | 0.83 | LPL (0.44) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL20512775 | 0.82 | LIPG (0.39) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL14707184 | 0.81 | LIPG (0.39) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL22748247 | 0.81 | LPL (0.61) | LIPGLPL | |
| SCHEMBL22768361 | 0.79 | LPL (0.37) | LIPGLPLF11ESR2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666541-B | Purine or deazapurine derivatives for the treatment of, in particular, viral infections | GILEAD SCIENCES, INC. (US) | 2015-11-25 | — | — | CN | disclosed |