Nitrosoguanidine

Nitrosoguanidine

SCHEMBL28033353

CC(C)=O.N=C(N)NN=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
ALOX15 P16050 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
PLK4 O00444 1/20 0.33
CHEK1 O14757 1/20 0.33
AURKA O14965 1/20 0.33
CHUK O15111 1/20 0.33
DAPK3 O43293 1/20 0.33
JAK2 O60674 1/20 0.33
ROCK2 O75116 1/20 0.33
PAK4 O96013 1/20 0.33
CHEK2 O96017 1/20 0.33
CDK1 P06493 1/20 0.33
PIM1 P11309 1/20 0.33
PRKACA P17612 1/20 0.33
FGFR3 P22607 1/20 0.33
RPS6KB1 P23443 1/20 0.33
CDK2 P24941 1/20 0.33
MARK3 P27448 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrosoguanidine SCHEMBL96467 0.89
Nitrosoguanidine SCHEMBL28164333 0.86
Nitrosoguanidine SCHEMBL27701011 0.80 ALDH1A1 (0.43) LMNA
Nitrosoguanidine SCHEMBL27533013 0.77 ALOX15 (0.31) ALOX15
Nitrosoguanidine SCHEMBL28028483 0.75 ALDH1A1 (0.33)
Nitrosoguanidine SCHEMBL11052225 0.70
Acetone SCHEMBL1277371 0.69
Ethane SCHEMBL8670767 0.69
SCHEMBL7859358 0.69 ALDH1A1 (0.46) LMNAALOX15BLMPMP22PLK4
SCHEMBL2949847 0.69 ALDH1A1 (0.46) LMNAALOX15BLMPMP22PLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105296463-A Method of acquiring 9Alpha-hydroxyandrostenedione high-yield strain HEBEI DARUI BIOTECH CO LTD 2016-02-03 CN claimed
CN-109266572-B Lactobacillus casei mutant strain for producing glutamine transaminase and application thereof 湖南肯基因科技有限公司 2021-06-29 CN disclosed
CN-109294940-B Lactobacillus zeae mutant strain and application thereof in high yield of lactic acid 湖南肯基因科技有限公司 2021-06-29 CN disclosed
CN-109097308-B Mutagenic strain for high yield of acid protease and application thereof 湖南肯基因科技有限公司 2021-06-29 CN disclosed
CN-109182171-B Mutagenic strain for high yield of gamma-aminobutyric acid and biological preparation thereof 湖南肯基因科技有限公司 2021-06-29 CN disclosed
CN-111139277-A Crude polysaccharide and preparation process thereof, health-care oral liquid and preparation method thereof 长春工业大学 2020-05-12 CN disclosed
CN-110592161-A Preparation method of polysaccharide, health-care oral liquid and preparation method 长春工业大学 2019-12-20 CN disclosed
CN-104480054-B A kind of bacterial strain and preparation method thereof of acid resistance high yield succinic acid 吉林农业大学 2018-07-27 CN disclosed