Sulfuric Acid

Sulfuric Acid

SCHEMBL28033719

O=S(=O)(O)O.Oc1c[nH]c2ccc(Cl)cc12

nearest known ligand 0.56

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.56
F3 P13726 1/20 0.56
GPR84 Q9NQS5 2/20 0.50
NR4A2 P43354 1/20 0.49
POLB P06746 1/20 0.46
DUSP3 P51452 1/20 0.46
PTPN5 P54829 1/20 0.46
PTPN11 Q06124 1/20 0.46
HTR2A P28223 2/20 0.45
TRPM8 Q7Z2W7 1/20 0.45
PIK3CA P42336 1/20 0.44
MTOR P42345 1/20 0.44
PIK3CG P48736 1/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
GABRP O00591 2/20 0.43
GABRD O14764 2/20 0.43
GABRA1 P14867 2/20 0.43
GABRB1 P18505 2/20 0.43
GABRG2 P18507 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17439076 0.91 F7 (0.59) F7F3GPR84NR4A2HTR2A
Sulfuric Acid SCHEMBL22441041 0.86 GPR84 (0.54) F7F3GPR84NR4A2
Phosphoric Acid SCHEMBL27944654 0.86 F7 (0.56) F7F3GPR84NR4A2HTR2A
SCHEMBL5730676 0.79 F7 (0.56) F7F3GPR84NR4A2POLB
Butyric Acid SCHEMBL28033714 0.79 F7 (0.55) F7F3GPR84NR4A2HTR2A
SCHEMBL154688 0.76 GPR84 (0.63) F7F3GPR84NR4A2
Indole SCHEMBL19836844 0.75 AHR (0.51) F7F3GPR84NR4A2POLB
Phosphoric Acid SCHEMBL27949425 0.74 POLB (0.45) F7F3GPR84NR4A2POLB
Sulfuric Acid SCHEMBL38066 0.74 SLC22A6 (0.56) GPR84
Sulfuric Acid SCHEMBL27181503 0.74 SLC22A6 (0.56) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102958584-B Filter plate article with water absorbent filter assembly 3M INNOVATIVE PROPERTIES CO. (US) 2015-10-21 CN disclosed