SCHEMBL28033840

SCHEMBL28033840

O=C(NC(Cl)Cl)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.63
HPGD P15428 2/20 0.63
ALDH1A1 P00352 6/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
HDAC3 O15379 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
IDO1 P14902 1/20 0.54
ALOX15 P16050 1/20 0.54
HDAC1 Q13547 1/20 0.54
CA9 Q16790 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HSD17B10 Q99714 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
NCOR2 Q9Y618 1/20 0.54
SLC1A2 P43004 1/20 0.53
CTRB1 P17538 3/20 0.52
MEN1 O00255 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815318 0.84 LMNA (0.61) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL10589495 0.83 LMNA (0.59) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL11568901 0.83 LMNA (0.59) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL28641833 0.81 HDAC3 (0.58) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL28274372 0.81 LMNA (0.58) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL27243970 0.81 LMNA (0.68) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL27244159 0.81 LMNA (0.58) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL4682930 0.79 LMNA (0.64) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL7529153 0.79 LMNA (0.56) LMNAHPGDALDH1A1SMN1; SMN2HDAC3
SCHEMBL28118956 0.79 HDAC3 (0.56) LMNAHPGDALDH1A1SMN1; SMN2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104559315-B Yellow mixed crystal type disperse dye 江苏迪安化工有限公司 2016-09-14 CN disclosed
CN-105153113-A 3, 5-thiobenzamide dihalide insecticide UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-12-16 CN disclosed
CN-103130770-B 3, 5-dihalogenated thiobenzamide pesticide QINGDAO UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2015-11-25 CN disclosed
CN-105085477-A Dihalopyridylpyrazolyl amide compounds and application thereof NANJING GUANGFANG BIOTECHNOLOGY CO LTD 2015-11-25 CN disclosed