Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589495 | 0.86 | LMNA (0.59) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL27244159 | 0.84 | LMNA (0.58) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL7529153 | 0.82 | LMNA (0.56) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL28033840 | 0.81 | LMNA (0.63) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL8234446 | 0.79 | GAA (0.56) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL9815318 | 0.79 | LMNA (0.61) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL4689548 | 0.78 | SMN1; SMN2 (0.53) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL4689551 | 0.78 | SMN1; SMN2 (0.53) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL11568901 | 0.78 | LMNA (0.59) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 | |
| SCHEMBL7208912 | 0.77 | LMNA (0.50) | LMNAHPGDALDH1A1SMN1; SMN2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369436-A | A kind of amide replaces alpine yarrow herb ketoacid derivatives and preparation method and purposes | 中国科学院新疆理化技术研究所 | 2019-02-22 | — | — | CN | disclosed |