Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.50 |
| ▸ | THRA | P10827 | 8/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258850 | 0.82 | AKR1B1 (0.46) | THRBTHRAAKR1B1KDM4EMAPT | |
| SCHEMBL15026095 | 0.80 | THRB (0.53) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL2921654 | 0.80 | HMGB1 (0.52) | THRBTHRAAKR1B1KDM4EMAPT | |
| SCHEMBL27846789 | 0.79 | NPSR1 (0.53) | THRBTHRA | |
| SCHEMBL4944685 | 0.78 | KDM4E (0.50) | THRBAKR1B1KDM4EMAPTHPGD | |
| SCHEMBL30354606 | 0.78 | KDM4E (0.50) | THRBAKR1B1KDM4EMAPTHPGD | |
| SCHEMBL25949767 | 0.77 | THRB (0.44) | THRBTHRAAKR1B1KDM4EMAPT | |
| SCHEMBL287411 | 0.77 | THRB (0.49) | THRBTHRAAKR1B1KDM4EPOLB | |
| SCHEMBL7073649 | 0.76 | THRB (0.61) | THRBTHRAHSD17B10TSHRPPARG | |
| SCHEMBL583915 | 0.75 | AKR1B1 (0.60) | THRBTHRAAKR1B1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870430-A | Herbicidally active cyclic dione compounds substituted by phenyl groups having alkynyl-containing substituents or derivatives thereof | SYNGENTA LTD | 2015-08-26 | — | — | CN | disclosed |