Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 15/20 | 0.77 |
| ▸ | INSR | P06213 | 6/20 | 0.77 |
| ▸ | IGF1R | P08069 | 5/20 | 0.77 |
| ▸ | EGFR | P00533 | 5/20 | 0.77 |
| ▸ | AURKA | O14965 | 1/20 | 0.77 |
| ▸ | ROS1 | P08922 | 1/20 | 0.77 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.77 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21846979 | 0.90 | EGFR (0.78) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL21709647 | 0.88 | ALK (0.87) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL26611528 | 0.88 | EGFR (0.79) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL21846992 | 0.87 | EGFR (1.00) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL29489146 | 0.87 | ALK (1.00) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL11916416 | 0.87 | ALK (1.00) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL29045219 | 0.87 | ALK (0.75) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL21847003 | 0.86 | ALK (0.74) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL22087542 | 0.86 | EGFR (1.00) | ALKINSRIGF1REGFRAURKA | |
| SCHEMBL30377478 | 0.86 | INSR (1.00) | ALKINSRIGF1REGFRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294759-A | Preparation method of antitumor drug | SOUTHEAST PHARMACEUTICALS CO LTD | 2016-02-03 | — | — | CN | disclosed |